RecruitingRecruiting
Identification of Genomic Predictors of Adverse Events After Cardiac Surgery
NCT01258231 · Brigham and Women's Hospital
In plain English
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About this study
This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure. In addition, we also examine blood and urine biomarkers (proteins).
Eligibility criteria
Inclusion Criteria:
* Undergoing heart surgery
* Willing to provide consent
Exclusion Criteria:
* Enrolled in a concurrent drug or device trial that precludes concurrent enrollment
Study design
Enrollment target: 4000 participants
Age groups: adult, older_adult
Timeline
Starts: 2000-08
Estimated completion: 2030-08
Last updated: 2024-08-22
Primary outcomes
- • Mortality (i.e. number of participants who are deceased during postoperative day 0 up to year 5) (Day of procedure to year 5)
Sponsor
Brigham and Women's Hospital · other
With: National Heart, Lung, and Blood Institute (NHLBI), Texas Heart Institute, University of Texas Southwestern Medical Center, Johns Hopkins University
Contacts & investigators
InvestigatorJochen D Muehlschlegel, MD MMSc, MPH · principal_investigator, Brigham and Women's Hospital
All locations (3)
Brigham and Women's HospitalCompleted
Boston, Massachusetts, United States
UT Southwestern Medical CenterRecruiting
Dallas, Texas, United States
Department Texas Heart Institute at St. Luke's Episcopal HospitalCompleted
Houston, Texas, United States