RecruitingRecruiting
Characterization of the Microbiome in Cutaneous T Cell Lymphoma
NCT03932279 · Northwestern University
In plain English
Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.
About this study
Investigators plan to perform a pilot study that aims to characterize the microbiome of human cutaneous T cell lymphoma patients and compare this to the microbiome of age and sex matched controls.
Eligibility criteria
Inclusion Criteria:
* Group 1: Patients with stage IA-IIA cutaneous T cell lymphoma
* Group 2: Patients with stage IIB and above cutaneous T cell lymphoma
* Group 3: Patients with CD30+ lymphoproliferative disorder including lymphomatoid papulosis and cutaneous anaplastic large cell lymphoma
* Group 4: Patients with plaque psoriasis with BSA\>5% on routine phototherapy per standard of care
* Group 5: Patients with moderate to severe atopic dermatitis on routine bleach bath therapy per standard of care
* Group 6: Healthy individuals without the above skin conditions, similar age and sex distribution to the patients with cutaneous T cell lymphoma
* All Groups: subjects who are age 18-89 years of age at time of enrollment
* All Groups: Subjects who are able and willing to give informed consent for this study and the Dermatology Tissue Acquisition and Biorepository (STU00009443).
Exclusion Criteria:
* All Groups: Subjects who are younger than 18 years of age or older than 90 years of age
* All Groups: Subjects who are unable to give consent
* Patients currently on systemic antibiotics or recent (within past 4 weeks) exposure to systemic antibiotics
* We will not recruit the following populations: adults unable to consent, individuals who are not yet adults (infants, children, teenagers), pregnant women, prisoners and other vulnerable populations.
Study design
Enrollment target: 300 participants
Age groups: adult, older_adult
Timeline
Starts: 2019-01-30
Estimated completion: 2028-08-31
Last updated: 2026-05-01
Primary outcomes
- • Bacterial diversity index (3 months)
Sponsor
Northwestern University · other
Contacts & investigators
ContactDermatology CTU · contact · NUderm-research@northwestern.edu · 312-503-5944
InvestigatorAlan Zhou, MD · principal_investigator, Northwestern University
All locations (1)
Northwestern UniversityRecruiting
Chicago, Illinois, United States