Recruiting

Incident Chronic Obstructive pulmoNary dIsease Cohort Study (ICONIC)

NCT04252781 · Assistance Publique - Hôpitaux de Paris

Recruiting

In plain English

Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.

About this study

A description of the population from which the groups or cohorts will be selected Smokers who have a screening spirometry for COPD, either in general medicine, at a pulmonologist or in the CHIC or Henri Mondor hospital respiratory function tests department. After screening, an equal number of men and women COPD will be included (150 men and 150 women). 1500 smokers will be included to reach 300 smokers with COPD.

Eligibility criteria

Inclusion Criteria: Inclusion criteria of smokers with spirometry (pre-inclusion) * Age\> 35 years * Smoking \> 20 PA * Active smoking (cessation \< 1 month) * Signature of consent to participate in Phase I of the study Inclusion criteria for patients with incidental COPD * FEV1 / FVC \<70% of the theoretical value and / or \<LLN (Lower limit of normal) * Signature of consent to participate in Phase II of the study Exclusion Criteria: * Known COPD * Cancer being treated * No affiliation to the social security or other social protection scheme * Pregnant or lactating woman * Patient deprived of liberty or under legal protection (under tutorship or curatorship

Study design

Enrollment target: 300 participants

Allocation: na

Masking: none

Age groups: adult, older_adult

Timeline

Starts: 2020-08-20

Estimated completion: 2026-02-20

Last updated: 2025-01-09

Interventions

Other: Exhaustive exploration

Primary outcomes

• 1-year adverse evolution (at 12 Months)

Sponsor

Assistance Publique - Hôpitaux de Paris · other

Contacts & investigators

ContactLaurent BOYER, MD · contact · laurent.boyer@aphp.fr · (0) 1 49 81 26 90

ContactLila KACI · contact · lila.kaci@aphp.fr · (0) 1 49 81 36 24

InvestigatorLaurent BOYER, MD · principal_investigator, Assistance Publique Hôpitaux de Paris (AP-HP)

All locations (1)

Hopital Henri MONDORRecruiting

Créteil, Île-de-France Region, France

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