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Integrated CBT to Improve Functioning in Veterans With Anxiety and Substance Use
NCT04871100 · VA Office of Research and Development
In plain English
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Official title
Addressing Mental Health Comorbidities: Integrated CBT to Improve Functioning in Veterans With Co-Occurring Anxiety and Substance Use
About this study
Co-occurring hazardous drinking, anxiety disorders, and PTSD are problematic combinations of mental health concerns experienced by deployed Veterans. Veterans who have been deployed are at particular risk for experiencing problems in functioning and reintegration related to mental health disorders and hazardous drinking. Co-occurring anxiety and hazardous drinking heavily impact psychosocial functioning and quality of life. Although cognitive behavior therapy (CBT) can promote psychological recovery through improvements in functioning and quality of life, most CBT protocols do not address co-occurring disorders, leading to inefficient and disjointed treatment. The current research seeks to adapt and test the Unified Protocol (UP) for deployed Veterans with hazardous drinking. The use of combined CBT for both anxiety disorders and hazardous drinking has the potential to more efficiently and effectively improve functioning, reduce symptoms, and promote psychosocial recovery.
Eligibility criteria
Inclusion Criteria:
* meeting diagnostic criteria for current anxiety disorder and
* endorsing hazardous alcohol use
Exclusion Criteria:
-need for acute medically-supervised detoxification with exclusionary criteria of
* high-risk suicidality
* psychotic symptoms, or
* cognitive impairment that could interfere with engagement in weekly psychotherapy
Study design
Enrollment target: 40 participants
Allocation: randomized
Masking: none
Age groups: adult, older_adult
Timeline
Starts: 2023-03-01
Estimated completion: 2026-10-01
Last updated: 2025-10-09
Interventions
Behavioral: Unified Protocol- AlcoholBehavioral: Usual care
Primary outcomes
- • Social Adjustment Scale- Self Report (2-weeks)
- • Beck Anxiety Inventory (past 30 days)
- • Addiction Severity Index (30 days)
Sponsor
VA Office of Research and Development · fed
Contacts & investigators
ContactAnthony Ecker, PhD · contact · anthony.ecker@va.gov · (713) 440-4400
InvestigatorAnthony Ecker, PhD · principal_investigator, Michael E. DeBakey VA Medical Center, Houston, TX
All locations (1)
Michael E. DeBakey VA Medical Center, Houston, TXRecruiting
Houston, Texas, United States