Study of Microbiological Diversity in Exhaled Air in COPD and Free of COPD

NCT05437198 · Centre Hospitalier Intercommunal Creteil

Recruiting

In plain English

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Official title

Study of Microbiological Diversity in Exhaled Air in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD) and Subjects Free of COPD

About this study

The subjects will be recruited during a medical visit in the Departments of Pneumology and Occupational and Environmental Pathologies. After information and inclusion of the subject in the study, a collection of clinical data, the state of health and the smoking status of the subject will be carried out by the clinical study technician. A collection of the exhalation will also be carried out by the clinical study technician. Several groups of subjects will be formed according to pathologies (COPD versus non-COPD), age and smoking status

Eligibility criteria

Inclusion Criteria: For COPD: * Patients with chronic obstructive pulmonary disease * Age: over 18 For non-COPD * Absence of chronic obstructive pulmonary disease * Age: between 18 and 30 years old and between 45 and 70 years old Exclusion Criteria: * Taking certain medications in the month preceding the sample (antibiotics, systemic corticosteroids, immunosuppressants) * Person under guardianship or curatorship * Pregnant or breastfeeding women * Person unable to express his/her opposition, person deprived of liberty * Existence of a chronic infectious pulmonary pathology such as (dilation of the bronchi, cystic fibrosis)

Study design

Enrollment target: 240 participants

Age groups: adult, older_adult

Timeline

Starts: 2024-03-26

Estimated completion: 2029-03

Last updated: 2025-06-12

Interventions

Other: collection of human exhalation

Primary outcomes

• Number and dominant bacterial species in human exhalations of COPD subjects and non-COPD subjects (Baseline)

Sponsor

Centre Hospitalier Intercommunal Creteil · other

Contacts & investigators

ContactJean-Claude PAIRON, PhD · contact · jc.pairon@chicreteil.fr · 01 45 02 20 93

ContactCamille JUNG, PhD · contact · camille.jung@chicreteil.fr · 0145175000

InvestigatorJean Claude PAIRON, PhD · principal_investigator, CHI créteil

All locations (1)

Centre Hospitalier Intercommunal de CréteilRecruiting

Créteil, France

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