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Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network
NCT05627219 · Thomas Jefferson University
In plain English
Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.
Official title
Peer Genetic Coaches for Enhancing Genetic Testing Awareness, Navigation, and Delivery Among African American Men With Metastatic Prostate Cancer, The EXPAND Network
About this study
PRIMARY OBJECTIVES:
I. Identify and train 6 African American (AA) men as peer genetic coaches (PGCs) for the Extending Prostate Genetic Awareness, Navigation, and Delivery (EXPAND) Network. (Train peer genetic coaches) II. Conduct a feasibility study of peer genetic coaching. (Provide individual coaching)
SECONDARY OBJECTIVE:
I. Patient-related outcomes will include change in decisional conflict for genetic counseling, acceptability/attitude toward genetic counseling and testing, and change of genetics knowledge.
OUTLINE:
AIM 1: Peer genetic coaches undergo training and education on study.
AIM 2: Patients receive an educational booklet and attend a discussion with a peer genetic coach on study.
Eligibility criteria
Inclusion Criteria:
* AIM 1: Are 18 years old or older
* AIM 1: Are able to read and speak English comfortably
* AIM 1: Men who have experience with both prostate cancer (PCA) and genetic counseling and testing will be a priority for training, as well as men who have considerable peer education or navigation experience
* AIM 2: Are 18 years old or older
* AIM 2: Are African American
* AIM 2: Are able to read and speak English comfortably
* AIM 2: Men who meet any one of the following criteria: (1) metastatic prostate cancer; (2) prostate cancer with high-risk features (T3 or higher, Gleason 8 or higher, node positive disease); (3) with or without a diagnosis of prostate cancer with strong family history (2 or more first-degree or second-degree relatives) with prostate cancer (particularly metastatic prostate cancer or died from prostate cancer), breast cancer, ovarian cancer, pancreatic cancer, colorectal cancer, uterine cancer, renal cancer, urothelial cancer, or upper bowel cancer
Exclusion Criteria:
* Patients that do not meet the inclusion criteria
* Children under the age of 18
* Anyone who has trouble understanding the consent or with significant anxiety detected during the consent process
Study design
Enrollment target: 30 participants
Age groups: adult, older_adult
Timeline
Starts: 2024-06-03
Estimated completion: 2026-04-29
Last updated: 2025-05-20
Interventions
Behavioral: Training and EducationOther: Educational InterventionProcedure: Discussion
Primary outcomes
- • Number of inquiries to the central number (feasibility) (Up to 1 year)
- • Percent of callers screened and eligible to participate (feasibility) (Up to 1 year)
- • Percent of eligible callers who enroll in the study (feasibility) (Up to 1 year)
Sponsor
Thomas Jefferson University · other
Contacts & investigators
ContactAmy Leader, DrPh, MPH · contact · amy.leader@jefferson.edu · 215 955-7739
InvestigatorAmy Leader, DrPh, MPH · principal_investigator, Thomas Jefferson University
All locations (1)
Sidney Kimmel Cancer Center at Thomas Jefferson UniversityRecruiting
Philadelphia, Pennsylvania, United States