RecruitingRecruiting
MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy
NCT05710380 · University of Chicago
In plain English
Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.
Official title
Magnetic Resonance Imaging (MRI) Derived Quantitative Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy
About this study
Doctors leading this study hope to learn about a software that researchers at the University of Chicago have developed to help analyze radiographic images (different techniques for taking images that allow doctors to visualize the body's internal structures) of the prostate. Participation in this research will last about 12 months. There is a one-time MRI and 1-2 biopsies and then the investigator would like to follow the participant's progress.
Eligibility criteria
Inclusion Criteria:
* Patients with known or suspected prostate cancer who have been referred for a diagnostic magnetic resonance imaging (MRI) exam of the prostate, to be followed by an MRI-guided fusion biopsy of the prostate.
* Voluntary written informed consent before the MRI examination.
Exclusion Criteria:
* Subjects incapable of giving informed written consent.
* Subjects who cannot adhere to the experimental protocols for any reason, or have an inability to communicate with the researcher;
* Subjects with psychiatric disorders that affect their ability to consent for themselves will be excluded and not the entire population of patients with psychiatric disorders.
* Prisoners.
* Minor children (under the age of 18 years old).
* Patients with previous treatments (surgery, radiation, focal ablation, hormone or other chemotherapy) for prostate cancer.
Study design
Enrollment target: 180 participants
Allocation: na
Masking: none
Age groups: adult, older_adult
Timeline
Starts: 2023-04-26
Estimated completion: 2029-05-01
Last updated: 2026-09-01
Interventions
Other: Risk Map Decision Support System (DSS).Radiation: Magnetic Resonance Imaging (MRI)Procedure: Magnetic Resonance Imaging (MRI) Guided Biopsy
Primary outcomes
- • Decision Map Tool Compared to Oncologists (1 year)
Sponsor
University of Chicago · other
With: National Cancer Institute (NCI)
Contacts & investigators
ContactAytekin Oto, MD · contact · aoto@radiology.bsd.uchicago.edu · 773-702-8553
InvestigatorAytekin Oto, MD · study_chair, University of Chicago Medicine Comprehensive Cancer Center
All locations (2)
University of Chicago Medicine Comprehensive Cancer CenterRecruiting
Chicago, Illinois, United States
Oregon Health & Science UniversityRecruiting
Portland, Oregon, United States