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MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
NCT05933083 · University of California, San Francisco
In plain English
Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.
About this study
Cardiac rehabilitation is a medically recommended program for patients with certain heart conditions. It includes exercise training, health education, and counseling. Unfortunately, many patients do not participate in cardiac rehabilitation. Some find it challenging to attend the in-person sessions. This study aims to compare two methods of delivering cardiac rehabilitation: in-person and through telehealth. The investigators want to know if the effects of these two programs are alike and if certain individuals benefit more from one program over the other.
Eligibility criteria
Inclusion Criteria:
1. Age 18 or older
2. Eligible for cardiac rehabilitation
1. Diagnosis within 1 year prior to consent
* Myocardial infarction
* Percutaneous coronary intervention
* Coronary artery bypass
* Heart valve repair or replacement
* Heart transplant
2. Chronic stable angina, or
3. Chronic systolic heart failure (ejection fraction ≤ 35%)
4. Referred to cardiac rehabilitation by a doctor or advanced practice provider for another indication that is covered by the participant's insurance, such as heart failure with preserved ejection fraction or aortic surgery.
3. Willing to be randomized to in-person or telehealth cardiac rehabilitation
4. Able to communicate in English or Spanish
Exclusion Criteria:
1. Unstable arrhythmias which may make unmonitored exercise unsafe (e.g., history of ventricular tachycardia not on medical therapy and without an implantable cardioverter defibrillator)
2. Unsafe for patient to participate in the opinion of the investigator
3. Hospice
4. Unable to consent for self
Study design
Enrollment target: 516 participants
Allocation: randomized
Masking: none
Age groups: adult, older_adult
Timeline
Starts: 2023-10-27
Estimated completion: 2027-10-15
Last updated: 2025-09-11
Interventions
Behavioral: In-person cardiac rehabilitationBehavioral: Telehealth cardiac rehabilitation
Primary outcomes
- • Change in six minute walk distance (Baseline and 12 months)
Sponsor
University of California, San Francisco · other
With: Patient-Centered Outcomes Research Institute, Mayo Clinic, University of Michigan, University of Pittsburgh, Johns Hopkins University
Contacts & investigators
ContactAlisa Boyd, MPH · contact · mcnairstudy@ucsf.edu · 415-502-6191
InvestigatorAlexis Beatty, MD, MAS · principal_investigator, University of California, San Francisco
All locations (5)
University of California, San FranciscoRecruiting
San Francisco, California, United States
Denver HealthRecruiting
Denver, Colorado, United States
Johns Hopkins University Medical CenterRecruiting
Baltimore, Maryland, United States
University of MichiganRecruiting
Ann Arbor, Michigan, United States
University of Pittsburgh Medical CenterRecruiting
Pittsburgh, Pennsylvania, United States