← Back to searchRecruitingRecruiting
Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness
NCT05962879 · Massachusetts General Hospital
In plain English
Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.
About this study
This research study aims to develop a brief group-based treatment called Resilience Training for Teens, then to test how well it protects high school students with mild symptoms of depression, anxiety, or having unusual feelings from developing mental illnesses.
Eligibility criteria
Inclusion Criteria:
* Currently enrolled in 9th through 12th grade and between the ages of 14 and 19
* Endorsed at least one psychotic experience
* Provided contact information
* Have a parent or legal guardian who is able and willing to provide written informed consent (if under the age of 18)
* Have a parent or legal guardian who is able and willing to participate in a parent session
* Competent and willing to provide written informed assent (if under the age of 18) or consent (if age 18 or older)
* Able to communicate in English
Exclusion Criteria:
* Currently prescribed psychotropic medication (not including medications for attention deficit/hyperactivity disorder), regardless of adherence
* Currently obtaining psychotherapeutic intervention
Study design
Enrollment target: 70 participants
Allocation: randomized
Masking: single
Age groups: child, adult
Timeline
Starts: 2024-03-22
Estimated completion: 2027-07-31
Last updated: 2025-12-09
Interventions
Behavioral: Resilience Training for Teens
Primary outcomes
- • Structured Interview of Psychosis-risk Syndromes (SIPS) (1 year)
Sponsor
Massachusetts General Hospital · other
With: National Institute of Mental Health (NIMH)
Contacts & investigators
ContactNicole R DeTore, PhD · contact · ndetore@mgh.harvard.edu · 617-726-2065
All locations (1)
Massachusetts General HospitalRecruiting
Boston, Massachusetts, United States