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Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)
NCT06315179 · Seattle Children's Hospital
In plain English
Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.
Official title
Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation
About this study
Research procedures will coincide with clinical visits at institutional standards. As part of their clinical disease evaluation, participants will have blood, stool, and tissue collected as indicated by their disease course. Additional research samples or data will be collected during these visits. Participants will be asked to collect urine samples specifically for research.
Eligibility criteria
Inclusion Criteria:
* Suspected diagnosis of CD (Crohn's Disease), UC (Ulcerative Colitis) or Indeterminate colitis (IC)
Exclusion Criteria:
* Evidence of Other Complicating Medical Issues:
* Other serious medical conditions, such as neurological, liver, kidney, or systemic disease
* Pregnancy
* Tobacco, alcohol, or illicit drug abuse
Study design
Enrollment target: 200 participants
Age groups: child, adult
Timeline
Starts: 2024-05-10
Estimated completion: 2030-01
Last updated: 2025-05-15
Interventions
Diagnostic Test: Esophagogastroduodenoscopy (EGD) with biopsyDiagnostic Test: Colonoscopy w/ biopsy
Primary outcomes
- • Bio-repository sample collection for spatial transcriptomics (3 years)
Sponsor
Seattle Children's Hospital · other
With: Allen Institute
Contacts & investigators
ContactMason E Nuding, BS · contact · mason.nuding@seattlechildrens.org · 206-987-0055
InvestigatorBetty (Hengqi) Zheng, MD · principal_investigator, Seattle Children's Hospital, University of Washington
All locations (1)
Seattle Children's HospitalRecruiting
Seattle, Washington, United States