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Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault

NCT06444295 · University of Washington
In plain English

Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.

Official title
Project THRIVE: Testing an App-based Early Intervention to Reduce Alcohol Use and PTSD After Sexual Assault
About this study
The goal of this study is to find the most effective and efficient version of the THRIVE app. The THRIVE app is the first app-based preventative intervention that has been found to reduce alcohol misuse and posttraumatic stress in people who have recently experienced sexual assault. In this trial, participants are randomly assigned to receive different versions of the THRIVE app to compare their impact. The THRIVE app is currently only available to participants in this study.
Eligibility criteria
Inclusion Criteria: * Have reached the legal age of majority in their current state of residence * Be able to read and speak English fluently * Own a smartphone that cannot be accessed by others while the study app is installed, or they agree to take steps to reduce the risk that someone else will access the study app * Be an enrolled undergraduate or graduate student at a recruitment site at the time of screening, or if they are on summer break, plan to be enrolled in the upcoming fall term * Reside in the same state as the recruitment site for most of the year * Have experienced a sexual assault (i.e., unwanted and non-consensual attempted/completed sexual contact) within the past 12 weeks at the time of screening * Report ≥1 past-month heavy drinking episode (i.e., 5+ drinks on a given day or 15+ drinks in a given week for participants assigned male at birth and 4+ drinks on a given day or 8+ drinks in a given week for participants assigned female or intersex at birth) at the time of screening * Endorse elevated posttraumatic stress symptoms at screening (defined as a score above a pre-established cut point on a screening measure of PTSD). Exclusion Criteria: * Active psychosis * Location outside of the US at the time of screening
Study design
Enrollment target: 464 participants
Allocation: randomized
Masking: none
Age groups: adult, older_adult
Timeline
Starts: 2024-07-29
Estimated completion: 2027-07-15
Last updated: 2025-02-11
Interventions
Behavioral: Activity schedulingBehavioral: Cognitive restructuringBehavioral: Coaching callsBehavioral: Non-core intervention components
Primary outcomes
  • Past-month alcohol problems (Baseline, 1 month, 3 months, 6 months, 9 months, 1 year)
  • Past-month number of drinks (Baseline, 1 month, 3 months, 6 months, 9 months, 1 year)
  • Past-month number of drinking days (Baseline, 1 month, 3 months, 6 months, 9 months, 1 year)
Sponsor
University of Washington · other
With: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Contacts & investigators
ContactEmily Dworkin, PhD · contact · edworkin@uw.edu · 206-503-3287
InvestigatorEmily Dworkin, PhD · principal_investigator, University of Washington
All locations (1)
University of WashingtonRecruiting
Seattle, Washington, United States
Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault · TrialPath