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Minimal Clinically Important Difference of the Box and Block Test in Parkinson

NCT06490809 · Karadeniz Technical University
In plain English

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Official title
Examining the Clinical Significance of the Change in Manual Dexterity of Parkinson's Patients Receiving Conventional Physiotherapy
About this study
The aim of this study is to examine the level of clinical change in gross manual skills of Parkinson's patients who receive conventional physiotherapy. For this purpose, the Box-Block Test will be used, and the amount of change that must occur in the patient's hand functions will be determined for the test to be considered clinically meaningful. Patients will continue their routine physical therapy sessions and the researchers will not interfere with this program. The treatment program will be created by the clinical specialist physician and physiotherapist. Upper extremity rehabilitation programs for Parkinson's patients generally consist of methods such as stretching, strengthening, reaching, coordination and recreational activities. Patients will receive physiotherapy for 30 sessions.
Eligibility criteria
Inclusion Criteria: * Being Hoehn \& Yahr Stage between 1-3, * Individuals in the "On" phase, * Those who were not exposed to any physiotherapy intervention during the initial assessment Exclusion Criteria: * Mini-mental status assessment \< 24 points; * Presence of severe dyskinesia, * Those who experience fluctuations in the on-off phase, * Those who have undergone stereotaxic brain surgery for Parkinson's, * Individuals with changes in dopamine dose within three months, * Presence of unstable cardiac and respiratory disease * Those with an orthopedic problem or a history of surgery affecting upper extremity performance.
Study design
Enrollment target: 44 participants
Allocation: na
Masking: none
Age groups: adult, older_adult
Timeline
Starts: 2024-10-01
Estimated completion: 2025-08-01
Last updated: 2025-03-05
Interventions
Other: Physiotherapy
Primary outcomes
  • Box and Block Test (Baseline of the study)
  • Box and Block Test (6 weeks (5 session days for 6 weeks))
  • Global Rating of Patient-Perceived Changes (GRP-PC) (6 weeks (5 session days for 6 weeks))
Sponsor
Emre Şenocak · other
Contacts & investigators
ContactEmre Şenocak, PhD · contact · emre.senocak@windowslive.com · +90 553 569 56 92
InvestigatorMurat Emirzeoğlu, PhD · study_chair, Karadeniz Technical University
InvestigatorTuğba Eyigürbüz, PhD · study_chair, Bağcılar Education and Research Hospital
InvestigatorAdem Aktürk, PhD · study_chair, İstanbul Gelişim University
All locations (1)
Özel Öz İstanbul Tıp MerkeziRecruiting
Istanbul, Turkey (Türkiye)
Minimal Clinically Important Difference of the Box and Block Test in Parkinson · TrialPath