← Back to searchRecruitingRecruiting
Improving Health Outcomes With Kefir
NCT06695221 · University of Alberta
In plain English
Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.
About this study
Participants who sign the written consent form will undergo a screening process to determine eligibility for study entry. At the baseline visit, recruited participants will be randomized in a double-blind manner (participant and study coordinator) to consume either 350 mL of traditional fermented kefir or 350 mL of a placebo (milk) daily. During the 12 weeks of intervention, health outcomes will be measured and collected for further analysis.
Eligibility criteria
Inclusion Criteria:
1. females and males (24-70 years old) living in Edmonton (or Edmonton area/driving distance);
2. overweight or obesity (BMI \>25 Caucasian, \>23 Asian);
3. at higher risk of T2D (fasting blood glucose ≥ 5.6 - 6.9 mmol/L or/and HbA1C ≥ 5.5 - 6.4%); or
4. with diagnosis of T2D (fasting blood glucose ≥ 7.0 mmol/L or/and HbA1C ≥ 6.5%).
Exclusion Criteria:
1. a usual high intake (maximum intake 3 servings/week) of fermented foods excluding cheese (i.e., kefir, kombucha, kimchi, etc.) for the past 3 months;
2. gastrointestinal (GI) disorders of any kind;
3. being pregnant or breastfeeding;
4. monogenic dyslipidemias and endocrine disorders except for diabetes;
5. use of medications within the last 3 months (i.e., antibiotics or antifungals, corticosteroids, methotrexate, or immunosuppressive cytotoxic agents);
6. any health conditions deemed to interfere with primary outcomes at the investigator's discretion (e.g., kidney disease, liver disease, cancer, GI surgery, heavy alcohol consumption, etc.);
7. having a pacemaker or any electrical medical device that prevents the individual from undergoing the bioelectrical impedance analysis bioimmunoassay (BIA) test."
Study design
Enrollment target: 156 participants
Allocation: randomized
Masking: double
Age groups: adult, older_adult
Timeline
Starts: 2026-03-24
Estimated completion: 2027-12
Last updated: 2026-03-12
Interventions
Dietary Supplement: Traditional KefirDietary Supplement: Milk (placebo)
Primary outcomes
- • Change in Glycated Hemoglobin (HbA1c) Levels (Percentage) (Baseline, 6 weeks, 12 weeks)
Sponsor
University of Alberta · other
Contacts & investigators
ContactPaulina Aldana Hernandez, PhD · contact · paldana@ualberta.ca · 780-492-9506
All locations (1)
University of AlbertaRecruiting
Edmonton, Alberta, Canada