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Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

NCT06698146 · Northwestern University
In plain English

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Official title
Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection Registry Study
About this study
Liver transplantation (LT) has become an accepted treatment for selected patients with unresectable liver metastases due to colorectal cancer (CRLM). The goal of this study is to look at and compare the clinical results of all the different approved methods (living vs. Deceased, whole organ vs. Split, one staged vs. Two staged) used to perform a standard liver transplant procedure for recipients with CRLM. Investigators will look at things like different procedure results, recovery in the hospital, and survival rates one year after the transplant. Investigators will also take blood samples from participants to be used in future research. All the transplant methods the investigators are comparing are standard practices approved by the United Network of Organ Sharing (UNOS).
Eligibility criteria
Inclusion: 1. All Patients of either gender ≥ 18 years of age who are listed for Liver transplant candidates at Northwestern with liver metastases due to colorectal cancer (CRLM). 2. Subjects must be able to provide informed consent themselves and without the use of a legally authorized representative (LAR), to be determined by the PI or Sub-I at the time of Consent. Exclusion: 1. Adults unable to consent 2. Pregnant Women 3. Certain clinical/surgical/anatomical parameters, at the discretion of the PI.
Study design
Enrollment target: 80 participants
Age groups: adult, older_adult
Timeline
Starts: 2025-08-27
Estimated completion: 2035-01-01
Last updated: 2026-02-10
Primary outcomes
  • Graft and Patient Survival Outcomes (From liver transplant to 12 months)
Sponsor
Northwestern University · other
Contacts & investigators
ContactYajaira Navarro · contact · a-daud@northwestern.edu · 312-694-2092
All locations (1)
Northwestern University-Comprehensive Transplant CenterRecruiting
Chicago, Illinois, United States
Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection · TrialPath