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Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
NCT06719583 · Michael J. Fox Foundation for Parkinson's Research
In plain English
Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.
Official title
Black and African Americans Connections to Parkinson's Disease (BLAAC PD) A Project of the Global Parkinson's Genetics Program (GP2)
About this study
Research studies have found connections between genes and Parkinson's disease (PD). But those results have mostly come from studies with non-Black or African American volunteers. BLAAC PD aims to learn more about gene changes that may cause Parkinson's in Black and African American people. Study volunteers at sites across the United States will attend one visit and will give either a blood or saliva sample, complete a smell test, and may be asked to complete a physical exam. This new data could lead to future Parkinson's tests and treatments for Black and African American people and it may help better understand disease in other groups, too.
This pioneering initiative will fill a gap of knowledge about PD in Black and African American people.
Eligibility criteria
Inclusion Criteria for Control Participants:
* Ability to provide informed consent
* Age 50 years or older
* Self-identify as Black or African American
Exclusion Criteria for Control Participants:
* Diagnosis of Parkinson's Disease and/or neurological condition
* Familial history of PD and/or neurodegenerative or psychiatric conditions
* Unknown family history of PD and/or neurodegenerative or psychiatric conditions
* Any conditions that, in the investigator's opinion, preclude the individual's ability to carry out study activities
* If submitting a saliva sample, nothing by mouth (food, drink, gum, tobacco, or smoking) for 30 minutes prior to sample collection
Inclusion Criteria for Participants with a Diagnosis of PD:
* Ability to provide informed consent
* Age 18 years or older
* Self-identify as Black or African American
* Meet the Movement Disorder Society's clinical diagnostic criteria for Parkinson's disease
Exclusion Criteria for Participants with a Diagnosis of PD:
\- If submitting a saliva sample, nothing by mouth (food, drink, gum, tobacco, or smoking) for 30 minutes prior to sample collection
Study design
Enrollment target: 2000 participants
Age groups: adult, older_adult
Timeline
Starts: 2020-11-16
Estimated completion: 2027-12-31
Last updated: 2026-02-27
Primary outcomes
- • Explore novel risk factors and characterization (5 years)
Sponsor
Michael J. Fox Foundation for Parkinson's Research · other
With: University of Chicago, University of Alabama at Birmingham, Rush University, Washington University School of Medicine, Medical University of South Carolina, University Hospitals Cleveland Medical Center, Louisiana State University Health Sciences Center Shreveport, University of Florida, University of Maryland, The University of Texas Health Science Center, Houston, Ochsner Health System, Indiana University
Contacts & investigators
ContactNaomi Louie, MPH RDN · contact · nlouie@michaeljfox.org · 212-509-0995
InvestigatorLana Chahine, MD, PhD · principal_investigator, University of Pittsburgh
All locations (12)
University of Alabama at BirminghamRecruiting
Birmingham, Alabama, United States
University of FloridaRecruiting
Gainesville, Florida, United States
Rush UniversityRecruiting
Chicago, Illinois, United States
University of ChicagoRecruiting
Chicago, Illinois, United States
Ochsner Clinic FoundationRecruiting
New Orleans, Louisiana, United States
Louisiana State University Health Sciences Center ShreveportRecruiting
Shreveport, Louisiana, United States
University of MarylandRecruiting
Baltimore, Maryland, United States
Kaiser Permanente Midatlantic StatesActive Not Recruiting
Rockville, Maryland, United States
Washington University in St. LouisRecruiting
St Louis, Missouri, United States
University Hospitals Cleveland Medical CenterRecruiting
Cleveland, Ohio, United States
Medical University of South CarolinaRecruiting
Charleston, South Carolina, United States
University of Texas Health Science Center, HoustonRecruiting
Houston, Texas, United States