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The Effect of Coconut Oil on Alopecia

NCT06818370 · Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
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Official title
The Effect of Coconut Oil on Alopecia in Women Receiving Doxorubucin-Cycylophosphamide Treatment for Breast Cancer
About this study
Cancer is a disease in which the cells in our body multiply uncontrollably and develop by metastasizing, and the symptoms, course and consequences of the disease can show complex qualities in each patient. Cancer treatments have benefits and harms. One of these side effects is alopecia. Alopecia due to cancer treatments is a condition of hair loss, partial or complete, usually temporary but rarely permanent. In chemotherapy-induced alopecia, the hair follicle is damaged due to the pause in the anagen phase and causes the hair to break off spontaneously during activities such as washing and brushing the hair. Various scales are used in the evaluation of alopecia due to cancer treatments, such as the National Cancer Institute Common Terminology Criteria for Side Effects and the Dean Alopecia Scale. Some applications are made to prevent and treat alopecia. These include strategies and pharmacological applications to physically reduce the amount of medication given to the hair follicle. Coconut oil helps regrow damaged hair. It provides essential proteins necessary for hair and softens the scalp and hair. In the literature, it has been observed that studies showing the effects of coconut oil for the prevention and treatment of alopecia are insufficient. This study will be conducted on 86 breast cancer patients to determine the effect of coconut oil on the development of alopecia.
Eligibility criteria
Inclusion Criteria: * • To have been diagnosed with breast cancer. * The chemotherapy treatment plan should be planned as the Doxorubicin-Cyclophosphamide protocol. * Volunteer to participate in the study. * Be 18 years of age or older. * Being a woman. Exclusion Criteria: * • Having any health problem or disability that prevents communication (vision-hearing problems, neurological, psychiatric diseases). * Planning other treatments other than the Doxorubicin-Cyclophosphamide protocol for the treatment of breast cancer. * Not volunteering to participate in the study. * Having previously experienced any disease/skin problem that causes hair loss. * Having received chemotherapy before.
Study design
Enrollment target: 86 participants
Allocation: randomized
Masking: single
Age groups: adult, older_adult
Timeline
Starts: 2025-02-03
Estimated completion: 2026-01-31
Last updated: 2025-02-12
Interventions
Other: Coconut Oil
Primary outcomes
  • National Cancer Instute (NCI) Common Terminology Criteria for Adverse Events (CTCAE); Alopecia (1-12 WEEK)
Sponsor
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · other
With: Çankırı Karatekin University
Contacts & investigators
Contactİsmail Dakdevir, Nurse · contact · dakdevirismail@gmail.com · +905533228416
All locations (1)
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Eğitim ve Araştırma HastanesiRecruiting
Ankara, Yenimahalle, Turkey (Türkiye)
The Effect of Coconut Oil on Alopecia · TrialPath