RecruitingRecruiting
A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial
NCT06822530 · Fred Hutchinson Cancer Center
In plain English
Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.
Official title
PROACT: Promoting Follow-Up of Abnormal Colorectal Cancer Screening Tests Through Multilevel Interventions
About this study
OUTLINE: Patients are randomized to 1 of 2 groups.
GROUP I: Patients receive usual care from the CRC screening program navigator which includes monthly phone calls with the CRC screening program navigator, and assistance with colonoscopy scheduling.
GROUP II: Patients receive usual care as described in Group I and additionally receive a quick response (QR) code with a link to a video to address patient-level fears of colonoscopy screening via text message, mailed letter, or EHR platform as well as access to transportation home after colonoscopy via a rideshare program arranged through the discharge nurse.
After completion of study intervention, patients are followed up for 18 months.
Eligibility criteria
Inclusion Criteria:
* PATIENTS: Age \>= 45 years old and =\< 75 years old
* PATIENTS: Receives care at an Harborview Medical Center (HMC) or University of Washington-Kent-Des Moines (UW-KDM) or University of Washington- Federal Way (UW-Federal Way) primary care clinic
* PATIENTS: \>= 1 month from documented abnormal FIT result
* PATIENTS: Has not received a colonoscopy between the abnormal FIT and enrollment
* CLINIC STAFF: HMC, UW-Federal Way, or UW-KDM physician or staff member who provides primary care or gastroenterology care
* CLINIC STAFF: Staff in the Fred Hutchinson (Fred Hutch)/UW Medicine Population Health Program that provide colorectal cancer screening and navigation
Study design
Enrollment target: 682 participants
Allocation: randomized
Masking: single
Age groups: adult, older_adult
Timeline
Starts: 2025-12-16
Estimated completion: 2030-01-31
Last updated: 2026-06-22
Interventions
Other: Best PracticeOther: Educational InterventionOther: Electronic Health Record ReviewOther: InterviewOther: Supportive CareOther: Survey Administration
Primary outcomes
- • Rate of colonoscopy completion within 6 months (At 6 months after randomization)
- • Time to colonoscopy completion (Beginning 6 months after randomization until study completion)
Sponsor
Fred Hutchinson Cancer Center · other
With: National Cancer Institute (NCI)
Contacts & investigators
ContactRachel B. Issaka, MD, MAS · contact · rissaka@fredhutch.org · 206-667-1447
InvestigatorRachel B. Issaka, MD, MAS · principal_investigator, Fred Hutch/University of Washington Cancer Consortium
All locations (1)
Fred Hutch/University of Washington Cancer ConsortiumRecruiting
Seattle, Washington, United States