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A Palliative Care Model Impact on Knowledge and Attitudes

NCT06860932 · Hunter College of City University of New York
In plain English

Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.

About this study
Patients will be asked for their goals-of-care preferences at baseline, after watching the video or reading the information sheet and after three months. Patients will be asked for their goals-of-care preference (Life-prolonging, Limited/Blended, Comfort, or Unsure), cardiopulmonary resuscitation (CPR) preference (Yes, No, or Unsure), and ventilatory support (Yes, No, or Unsure) at baseline, and then again immediately after watching the video or reviewing the informational sheet, and then the investigators will contact all patients after 3 months by telephone to ask for their preferences again. The investigators will also have an open-ended question for those subjects who change their preferences from the initial post-video or control survey ("Can patients tell us more about why they have changed their preference from the one stated before?"). The primary outcome is patient treatment preferences (i.e., care considerations, discontinuation of care, versus continued full care) for neurological care (Aim 1). The preferences will be measured as a binary outcome based on our clinical experience. When a patient chooses "" as an option for any of the treatment outcomes, in clinical care that is equivalent to the default (i.e., full code or life-prolonging interventions). Secondary outcomes include knowledge, decisional conflict, and preparation for decision making (Aims 1). The investigators will also explore the stability of preferences and documentation after 3 months (Aim 2). In all of investigators' prior trials, 3 months has been the requisite amount of time needed for patients to contemplate their decisions regarding medical care.
Eligibility criteria
Inclusion Criteria: * Diagnosed with MS, NMOSD, or anti-MOG, at least 2 years after their diagnosis. * Aged 18-65 * Speak English since all instruments are available in English. Exclusion Criteria: * Visually impaired (note, hearing impaired is not an exclusion criterion as the video is closed captioned). * Psychological state not appropriate for PC discussions as determined by the Patient Health Questionnaire 9 (PHQ9). * A score of 11 or higher, indicative of major depressive disorder, will be referred to immediate management and excluded from the study. * Unable to participate in PC discussions due to cognitive impairment as determined by the Processing Speed Test (PST) score below -1.5 Z score.
Study design
Enrollment target: 50 participants
Allocation: randomized
Masking: none
Age groups: adult, older_adult
Timeline
Starts: 2025-02-01
Estimated completion: 2026-06-30
Last updated: 2025-09-16
Interventions
Behavioral: Palliative care video comprises the conversation and advance directives.Behavioral: Palliative care written material
Primary outcomes
  • Palliative care preferences (i.e., care considerations, discontinuation of care, versus continued full care) for neurological care (Aim 1). (3 months.)
Sponsor
Hunter College of City University of New York · other
With: National Center for Advancing Translational Sciences (NCATS)
Contacts & investigators
ContactAliza Ben-Zacharia, PhD · contact · ab1288@hunter.cuny.edu · 6462262616
All locations (2)
Judith Jaffe Multiple Sclerosis CenterRecruiting
New York, New York, United States
Hunter CollegeRecruiting
New York, New York, United States
A Palliative Care Model Impact on Knowledge and Attitudes · TrialPath