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Effectiveness of Functional Respiratory Muscle Training in Post-COVID-19 Syndrome

NCT07051954 · Hacettepe University
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Official title
Investigation of the Effects of Functional Respiratory Muscle Training on Respiratory Muscle Function, Exercise Capacity, Skeletal Muscle Strength, and Muscle Endurance in Individuals With Post-COVID-19 Syndrome
About this study
This study aims to investigate the effects of core stabilization programs supported by core stabilization exercises and functional inspiratory muscle training (IMT) on various physiological and psychological parameters in individuals with post-COVID-19 syndrome. Participants to be included in the study will consist of individuals diagnosed with post-COVID syndrome and will be divided into two groups with a computer-aided stratified randomization method. After the patients are randomly separated, one group will receive 8 weeks of core stabilization training and the other group will receive functional IMT (IMT combined with core stabilization) training. The exercise program is designed to last 8 weeks in total, and the training program for both groups will be carried out on certain days (3 days) per week, and each session will last 50 minutes. A comprehensive assessment will be applied to both groups at the beginning and end of the study. These assessments are; exercise capacity, respiratory muscle strength, peripheral muscle strength, trunk muscle endurance, balance, anxiety and depression levels, and fatigue level parameters. The primary outcome measure of the study will be respiratory muscle strength and trunk muscle endurance. Individuals who meet the inclusion criteria will be included in the study. The study will be conducted with individuals between the ages of 18-65, with at least primary school education, and whose local language is Turkish. Participants diagnosed with Post-COVID-19 Syndrome and who are in class 2-3 according to the Post-COVID-19 Functional Status Scale (PCFS) will be included in the study. Participants who are eligible for the study will be directed to the Cardiopulmonary Rehabilitation Unit of the Hacettepe University Faculty of Physical Therapy and Rehabilitation by the relevant physicians of the Department of General Internal Medicine of the Hacettepe University Department of Internal Medicine.
Eligibility criteria
Inclusion Criteria: * Diagnosed with Post-COVID-19 Syndrome. * Literate and able to understand study procedures. * Aged between 18 and 65 years. * Willing to voluntarily participate in the study. * Classified as functional class 2-3 according to the Post-COVID-19 Functional Status Scale (PCFS). * Clinically stable; comorbid conditions such as hypertension or diabetes must be controlled. * No orthopedic or neurological conditions that would prevent assessment of peripheral muscle strength, balance, or exercise capacity. Exclusion Criteria: * History of recent myocardial infarction or pulmonary embolism. * Presence of uncontrolled chronic diseases. * Any orthopedic or neurological disorders that limit mobility. * Neurological impairments (e.g., cerebrovascular disease) or psychiatric disorders that impair cooperation or compliance with exercise testing.
Study design
Enrollment target: 40 participants
Allocation: randomized
Masking: single
Age groups: adult, older_adult
Timeline
Starts: 2025-09-15
Estimated completion: 2026-12-30
Last updated: 2026-01-14
Interventions
Other: Core StabilizationOther: Functional Inspiratory Muscle Training (IMT)
Primary outcomes
  • Respiratory muscle strength (Baseline and after 12 weeks of intervention.)
  • Plank Endurance Test (Baseline and after 12 weeks of intervention.)
  • Sorenson Endurance Test (Baseline and after 12 weeks of intervention.)
Sponsor
Hacettepe University · other
Contacts & investigators
ContactEbru Calik, PhD · contact · ecalik85@gmail.com · +905442850087
InvestigatorEBRU CALIK, Professor · principal_investigator, Hacettepe University
All locations (1)
Hacettepe UniversityRecruiting
Ankara, Çankaya, Turkey (Türkiye)
Effectiveness of Functional Respiratory Muscle Training in Post-COVID-19 Syndrome · TrialPath