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Combined Effects of Transcutaneous Electrical Diaphragmatic Stimulation With ACBT'S in Copd
NCT07079553 · Riphah International University
In plain English
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Official title
Combined Effects of Transcutaneous Electrical Diaphragmatic Stimulation With ACBT's in COPD
About this study
This study investigates the effectiveness of combining transcutaneous electrical diaphragmatic stimulation (TEDS) with active cycle of breathing techniques (ACBTs) in the management of chronic obstructive pulmonary disease (COPD). COPD is a progressive respiratory condition characterized by airflow limitation, respiratory muscle weakness, and reduced quality of life. Non-pharmacological interventions like pulmonary rehabilitation, including TEDS and ACBT, have shown individual benefits in improving lung function and exercise tolerance in COPD patients. However, the combined effect of these interventions has not been extensively studied.
The research was designed as a randomized controlled trial conducted at Gulab Devi Hospital, Lahore. A total of 50 patients diagnosed with mild to moderate COPD, aged between 40 and 60 years, were recruited based on defined inclusion and exclusion criteria. Participants were randomly assigned to two groups: Group A received a combination of TEDS and ACBT, while Group B received ACBT alone. The intervention lasted for 12 weeks. TEDS was applied using specific settings-50Hz frequency, 300ms width, 6 seconds of stimulation followed by 5 seconds of rest. ACBT was administered through structured sessions involving breathing control, thoracic expansion, and forced expiratory techniques.
Outcome measures included forced expiratory volume in one second (FEV₁), forced vital capacity (FVC), FEV₁/FVC ratio, oxygen saturation (both at rest and post-exercise), six-minute walk test (6MWT) distance, and the St. George's Respiratory Questionnaire (SGRQ) for quality of life assessment. Data analysis was performed using SPSS version 25, and non-parametric tests were applied due to non-normal data distribution.
Eligibility criteria
Inclusion Criteria:
* COPD (Mild to Moderate)
* Age: 40-60 years of both genders
* Productive cough for more than 2 months
* Oxygen saturation without Oxygen supply \> 88%
Exclusion Criteria:
* Uncontrolled hypertension
* Cardiac diseases
* Active smokers
Study design
Enrollment target: 50 participants
Allocation: randomized
Masking: double
Age groups: adult
Timeline
Starts: 2025-05-28
Estimated completion: 2025-11-10
Last updated: 2025-07-23
Interventions
Device: Transcutaneous Electrical Diaphragmatic Stimulation (TEDS)Behavioral: Active Cycle of Breathing Techniques (ACBT)
Primary outcomes
- • Forced Expiratory Volume in 1 second (FEV1) using Spirometry (12 weeks)
- • Forced Vital Capacity (FVC) using Spirometry (12 weeks)
- • FEV1/FVC Ratio using Spirometry (12 weeks)
Sponsor
Riphah International University · other
Contacts & investigators
Contactimran amjad, phd · contact · imran.amjad@riphah.edu.pk · 03324390125
InvestigatorArjumand Bano, MS-CPPT · principal_investigator, Riphah International University
All locations (1)
ArjumandRecruiting
Lahore, Punjab Province, Pakistan