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Recruiting

Second Prospective Cohort of Patients Entering the Multidisciplinary Care Pathway for Post-Covid Syndromes - SyPoCo2 Cohort

NCT07356570 · Hospices Civils de Lyon
In plain English

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About this study
The study aims to identify clinical profiles of long-COVID patients and correlate them with immunological and molecular data in order to identify prognostic biomarkers and potential therapeutic targets.
Eligibility criteria
Inclusion Criteria: * Documented SARS-CoV-2 infection * Persistent or complex post-COVID symptoms lasting more than 4 weeks or more than 3 months * Patient referred to the EPSILON pathway or to the post-COVID rehabilitation unit * Age ≥ 18 years * Non-institutionalized * Expected survival greater than 6 months Exclusion Criteria: * Refusal to participate or to share data * Uncontrolled comorbidities * Pregnant or breastfeeding women * Persons under legal protection or deprived of liberty * Not affiliated with the French national health insurance system
Study design
Enrollment target: 150 participants
Age groups: adult, older_adult
Timeline
Starts: 2025-06-13
Estimated completion: 2026-06
Last updated: 2026-01-21
Interventions
Other: Blood sample collection
Primary outcomes
  • Number of participants per clinical cluster at Day 0 (clusters derived from unsupervised multivariate analysis of clinical and paraclinical variables). (At inclusion (Day 0), single time point)
Sponsor
Hospices Civils de Lyon · other
Contacts & investigators
ContactSébastien Couraud, Pr · contact · Sebastien.couraud@chu-lyon.fr · 04 78 86 44 01
All locations (2)
Service Pneumologie aigue spécialisée et cancérologie thoraciqueRecruiting
Pierre-Bénite, France
Hôpital Henry Gabrielle-HCLRecruiting
Saint-Genis-Laval, France
Second Prospective Cohort of Patients Entering the Multidisciplinary Care Pathway for Post-Covid Syndromes - SyPoCo2 Cohort · TrialPath