RecruitingRecruiting
Delivery of a Culturally Tailored Exercise Training Intervention for Hispanics With Multiple Sclerosis
NCT07606742 · The University of Texas Health Science Center, Houston
In plain English
Click the button to translate this study into plain language — what it is, who qualifies, and what participation looks like.
About this study
The purpose of this study is to establish differences in the primary outcome of walking dysfunction using the 12-Item Multiple Sclerosis Walking Scale (MSWS-12) and to establish differences in the secondary outcome of HRQoL using the 29-Item Multiple Sclerosis Walking Scale (MSWS-29) between the exercise training intervention condition and the waitlist control condition following the 16-week intervention period.
Eligibility criteria
Inclusion Criteria:
* diagnosis of MS
* relapse-free in the past 30 days
* self-identify as Hispanic/Latino
* Patient Determined Disease Steps Scale (PDDS) score between 3.0 (gait disability) and 6.0 (bilateral support) indicates walking disability.
* MSWS-12 score between 25 and 75, indicating walking disability
* Willingness to complete the questionnaires and undergo randomization
* English or Spanish as a primary language
Exclusion Criteria:
* significant exercise-related risk factors or contraindications, assessed individually using the Physical Activity Readiness Questionnaire (PAR-Q; requires clearance from physician).
Study design
Enrollment target: 66 participants
Allocation: randomized
Masking: double
Age groups: adult, older_adult
Timeline
Starts: 2026-09-01
Estimated completion: 2028-10-31
Last updated: 2026-08-06
Interventions
Behavioral: Exercise Training
Primary outcomes
- • Change in walking ability as assessed by the 12-Item Multiple Sclerosis Walking Scale (MSWS-12) (Baseline, 16 weeks, 32 weeks)
Sponsor
The University of Texas Health Science Center, Houston · other
With: National Institutes of Health (NIH)
Contacts & investigators
ContactStephanie L Silveira, PhD · contact · Stephanie.L.Silveira@uth.tmc.edu · (713) 500-9490
ContactNajha Black · contact · Najha.C.Marshall@uth.tmc.edu · 713-500-9154
InvestigatorStephanie L Silveira, PhD · principal_investigator, The University of Texas Health Science Center, Houston
All locations (1)
The University of Texas Health Science Center at HoustonRecruiting
Houston, Texas, United States