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Recruiting

A Registry for People With Lung Cancer

NCT06424327 · Memorial Sloan Kettering Cancer Center
In plain English

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Official title
Pulmonary Segmentectomy for Lung Cancer: A Real-World International Registry-TSOG 108
About this study
Participants will complete questionnaires before surgery, between 2 to 4 weeks after surgery, and 6 months after surgery.
Eligibility criteria
Inclusion Criteria: * Age ≥18 years * Patients suitable for segmentectomy, according to the treating surgeon * Clinical Stage I with suspected NSCLC, classified preoperatively based on the AJCC TNM staging manual, 9th edition o Note: Tissue diagnosis of NSCLC is not required before enrollment. A pathologic diagnosis of NSCLC may be confirmed preoperatively with biopsy, intraoperatively with frozen section, or postoperatively on final pathology Exclusion Criteria: * Actively receiving lung cancer treatment or a history of lung cancer in the previous 5 years * History of chemotherapy or radiation therapy for a previous lung cancer * Synchronous secondary cancer in the lung or elsewhere in the body at the time of surgery * Carcinoid tumors * History of other malignancies within the past 3 years, with the exception of non-melanoma skin cancer, superficial bladder cancer, and carcinoma in situ of the cervix * Actively receiving treatment for other malignancies * Cases of lobectomy in conjunction with segmentectomy from another lobe and ≥2 segmentectomies from different lobes either en bloc or separate will be excluded from the primary analysis. * Multi-segmental resection from the same lobe is not a criterion for exclusion.
Study design
Enrollment target: 600 participants
Age groups: adult, older_adult
Timeline
Starts: 2024-05-15
Estimated completion: 2029-05-15
Last updated: 2026-09-17
Interventions
Other: Patient-Reported Outcomes Measurement Information System
Primary outcomes
  • Determine 3-year disease-free survival/DFS among patients undergoing pulmonary segmentectomy for lung cancer. (3 years)
  • Determine 5-year disease-free survival/DFS among patients undergoing pulmonary segmentectomy for lung cancer. (5 years)
Sponsor
Memorial Sloan Kettering Cancer Center · other
Contacts & investigators
ContactDavid Jones, MD · contact · jonesd2@mskcc.org · 212-639-6428
ContactBernard Park, MD · contact · parkb@mskcc.org · 646-888-3346
InvestigatorDavid Jones, MD · principal_investigator, Memorial Sloan Kettering Cancer Center
All locations (19)
University of Arizona (Data Collection Only)Recruiting
Tucson, Arizona, United States
University of California San Diego (Data collection)Recruiting
San Diego, California, United States
Rush University Medical Center (Data collection only)Recruiting
Chicago, Illinois, United States
Endeavor HealthRecruiting
Evanston, Illinois, United States
Massachusetts General Hospital Cancer Center (Data Collection Only)Recruiting
Boston, Massachusetts, United States
University of Michigan (Data Collection Only)Recruiting
Ann Arbor, Michigan, United States
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)Recruiting
Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Recruiting
Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)Recruiting
Montvale, New Jersey, United States
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)Recruiting
Commack, New York, United States
Memorial Sloan Kettering Westchester (Limited Protocol Activities)Recruiting
Harrison, New York, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)Recruiting
New York, New York, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Recruiting
Uniondale, New York, United States
Thomas Jefferson University Hospital (Data Collection Only)Recruiting
Philadelphia, Pennsylvania, United States
ALLEGHENY HEALTH NETWORK (Data Collection Only)Recruiting
Pittsburgh, Pennsylvania, United States
Baylor University Medical Center (Data Collection Only)Recruiting
Dallas, Texas, United States
MD Anderson Cancer Center (Data Collection Only)Recruiting
Houston, Texas, United States
University Health Network (Data Collection Only)Recruiting
Toronto, Ontario, Canada
Centre Hospitalier de l'Université de Montreal (Data Collection Only)Recruiting
Montreal, Quebec, Canada