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Systemic Immune Inflammatory Index in Systemic Lupus Erythematosus
NCT06796569 · Sohag University
In plain English
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Official title
Association of Systemic Immune Inflammatory Index with Disease Activity and Lupus Nephritis in Patients with Systemic Lupus Erythematosus
About this study
This study aims to investigate the association between the systemic immune-inflammation index and disease activity, as well as lupus nephritis in patients with systemic lupus erythematosus
Eligibility criteria
Inclusion Criteria:
* o Older than 16 years
* In a patient with SLE, patients who fulfill the criteria of the American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR).
* In patients with LN, patients whose diagnosis is confirmed by kidney biopsy and pathohistological verification (WHO classification, and the International Society of Nephrology/Renal Pathology Society (ISN/RPS) classification.
Exclusion Criteria:
* Patients with other autoimmune rheumatological diseases, lymphoproliferative disorders, malignancies, liver diseases, end-stage kidney disease, diabetic nephropathy, active infections, recent history of blood transfusion and patients with deficiencies in vitamin B12, folate, and iron are excluded from the study.
Study design
Enrollment target: 90 participants
Age groups: child, adult, older_adult
Timeline
Starts: 2024-12-02
Estimated completion: 2026-02
Last updated: 2025-01-28
Interventions
Diagnostic Test: systemic immune inflammatory index
Primary outcomes
- • association of systemic immune-inflammation index (SII) disease activity in systemic lupus erythematosus (baseline)
- • association of systemic immune-inflammation index (SII) and lupus nephritis in patients with systemic lupus erythematosus (baseline)
Sponsor
Sohag University · other
Contacts & investigators
ContactShorouk Mohamed abdelmageed, master degree · contact · Shrouk011107@med.sohag.edu.eg · 02 +01099082079
All locations (1)
Sohag FacultyRecruiting
Sohag, Sohag Governorate, Egypt